Interaction of Chlamydia psittaci with mouse peritoneal macrophages
نویسندگان
چکیده
منابع مشابه
Innate immune response in avian macrophages elicited by Chlamydia psittaci Aangeboren immuniteit van aviaire macrofagen geïnduceerd door Chlamydia psittaci
Chlamydia psittaci is a gram-negative, obligate, intracellular bacterium, which mainly infects birds and mammals. Not much is known about innate immunity initiated by C. psittaci. The focus of the present study is on chicken macrophage activation and expression of cytokine, chemokine, caspase-1, iNOS and TLR genes during the early phase and mid-cycle period of the developmental cycle of the hig...
متن کاملResponse of C3H/HeJ and C3H/HeN mice and their peritoneal macrophages to the toxicity of Chlamydia psittaci elementary bodies.
Intravenous injection of toxic doses of Chlamydia psittaci elementary bodies into endotoxin-responsive C3H/HeN mice or endotoxin-nonresponsive C3H/HeJ mice resulted in essentially identical time intervals to death. Inoculation of monolayer cultures of thioglycolate-stimulated peritoneal macrophages from the two strains of mice with 250 elementary bodies per macrophage resulted in immediate host...
متن کاملApoptosis of epithelial cells and macrophages due to infection with the obligate intracellular pathogen Chlamydia psittaci.
We have characterized the cytotoxic activity of the obligate intracellular bacterium Chlamydia psittaci, which resides within a membrane-bound vacuole during the 2-day infection cycle. We have established that infected epithelial cells and macrophages die through apoptosis, which is measurable within 1 day of infection and requires productive infection by the bacteria. Inhibition of host cell p...
متن کاملModulation of P2Z/P2X(7) receptor activity in macrophages infected with Chlamydia psittaci.
Given the role that extracellular ATP (ATP(o))-mediated apoptosis may play in inflammatory responses and in controlling mycobacterial growth in macrophages, we investigated whether ATP(o) has any effect on the viability of chlamydiae in macrophages and, conversely, whether the infection has any effect on susceptibility to ATP(o)-induced killing via P2Z/P2X(7) purinergic receptors. Apoptosis of ...
متن کاملSubacute thyroiditis associated with Chlamydia psittaci infection.
A patient presenting with subacute thyroiditis who had evidence of chlamydial infection is reported.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1978
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.19.3.1061-1067.1978